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WATCH NOW
Date & Time:
September 7, 2023
11 am ET | 8 am PT | 5 pm CET
Abstract:
This webinar would detail the importance of choosing a correctly sized/configured oligosynthesizer for your scale-up process (‘synth core’), the criticality of leaning on automation to define/edit the synthesis methods (molar EQs) and considerations for optimizing coupling efficiency to increase productivity.
Oligonucleotide producers looking to scale-up from laboratory to commercial manufacturing processes need to ensure that they choose a correctly sized and configured oligosynthesizer because otherwise their process will be inefficient, leading to unnecessary waste and reduced productivity.
Synthesis problems can stem from a lack of robust automation software used to build the methods, poorly defined parameters and a complex, difficult-to-navigate user interface.
Productivity can be severely hampered by amidite coupling inefficiency, which must be properly monitored and controlled throughout the synthesis process.
This webcast will detail how to choose the correctly sized oligosythesizer for your scale-up process, the criticality of leaning on automation to define/edit the synthesis methods and considerations for optimizing coupling efficiency to increase productivity.
Key Takeaways:
Using the right equipment for your specific manufacturing process can substantially increase product safety, process efficiency and overall productivity.
Manufacturing oligonucleotides at a commercial level can present different challenges than the lab environment – collaboration with experienced partners is a key to success
OLIGO Bigger, Faster, Further
Speakers:
Cory Hinz is the Engineering Manager at Asahi Kasei Bioprocess America, Inc. He received his Bachelor of Science (B.S.) in Mechanical Engineering from the University of Illinois at Urbana-Champaign. He is a certified professional engineer from the issuing authority of the Illinois Department of Financial and Professional Regulation.
George Flores is the Technical Solutions Manager at Asahi Kasei Bioprocess America, Inc. He provides creative and tailored product solutions, enabling streamlined manufacturing platforms for clients around the globe. He received his Bachelor of Science (B.S.) in Mechanical Engineering from Texas A&M University and Master of Business Administration (MBA) in Marketing from the Kellogg School of Management at Northwestern University.
Stefan Hyde is the Automation Manager for Asahi Kasei Bioprocess America, Inc. and an active participant in BioPhorum’s Plug and Play workstream in the Technology Roadmapping group. He has over a decade of experience with automated equipment in the pharmaceutical industry, starting his career in process engineering before transitioning to automation. He received his Master of Science (M.S.) in Mechanical Engineering with a field of study on controls and an Engineering Management Minor from Northwestern University.